exoLinc-p21s: a short lincRNA-p21-engineered exosome as a chemosensitizer for targeting DDB2-mediated DNA repair

First Author / 第一作者

Yu-Hao He

Institution / 單位

Center for Molecular Medicine, China Medical University Hospital, Taichung, 40402, Taiwan

Audio / 音訊檔

Author Group / 作者群

Yu-Hao He1†, Ming-Hsin Yeh2, Ya-Ling Wei1, Shu-Wei Hu1, Thanh Kieu Huynh1, Fang-Ju Cheng1, Dai-Wei Hu1, Yi-Lun Yeh1, Jai-Sing Yang3, Ming-You Shie4, Yun-Ju Chen5, Ya-Jen Chang6, Chun-Hsu Yao7, Der-Yang Cho8, and Wei-Chien Huang1*

Author Group Institution/ 作者群單位

1 Center for Molecular Medicine, China Medical University Hospital, Taichung, 40402, Taiwan 2 Department of Surgery, Chung Shan Medical University Hospital, Taichung, 40201, Taiwan 3 Department of Medical Research, China Medical University Hospital, Taichung, 40447, Taiwan 4 x-Dimension Center for Medical Research and Translation, China Medical University Hospital, Taichung, 404332, Taiwan 5 Department of Medical Research, E-Da Hospital, Kaohsiung, 82445, Taiwan 6 Institute of Biomedical Sciences, Academia Sinica, Taipei, 11529, Taiwan 7 Biomaterials Translational Research Center, China Medical University Hospital, Taichung, 40447, Taiwan 8 Drug Development Center, China Medical University, Taichung, 40402, Taiwan

Category / 主題分類

Basic Research

Keyword / 關鍵字

Chemosensitizer, DNA repair, LincRNA-p21, Macromolecular docking, Exosomal-RNA delivery system

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